Allumiqs is a Registered Supplier on Scientist.com

High Sensitivity Biomarker Assay

Unprecedented Sensitivity with ARGO™ HT + NULISA™

Our High Sensitivity Biomarker Assay combines the power of the ARGO™ HT system with NULISA™—a next-gen immunoassay platform that achieves attomolar-level detection. Built on Alamar Biosciences’ dual-capture-and-release innovation, this assay delivers ultra-low detection limits and broad multiplexing for critical biomarkers in plasma, CSF and other biofluids, as well as some critical tissues such as brain homogenates.

Get to know ARGO™ HT

Ultra-Sensitive Low-Level Protein Detection

  • A fully automated, immuno‑sandwich based assay using oligonucleotide‑linked antibodies and dual magnetic capture to suppress background noise and enhance sensitivity 10,000‑fold over conventional proximity assays
  • Designed for single-plex or high‑plex detection, enabling quantitation of dozens to hundreds of proteins in one run
  • Compatible with immuno-sequencing readout for high‑plex panels (e.g., 200+ targets) 

Delivering Data Analysis that Drives Discovery

At Allumiqs, data is not just a byproduct – it’s the engine of insight. Our enriched data analysis transforms raw datasets into actionable intelligence, empowering you to make confident, informed decisions faster.

  • Expertise that goes beyond the numbers: a dedicated team of data scientists and platform specialists that contextualize, validate, and interpret the results generated in our High Sensitivity Biomarker Assay solutions.
  • Data quality: 25 embedded checkpoints to ensure data integrity and quality.
  • Interactive data visualization: We deliver results in intuitive, interactive formats so that you can fully explore your data.
  • Interpretation & Reporting: Our reports go beyond basic charts and tables. We provide context for the story of your research and next-step recommendations.

How It Works

  1. ARGO™ HT automation for high-throughput liquid handling and assay setup
  2. Dual magnetic capture:
    • First with oligo-dT beads targeting DNA-tagged antibodies;
    • After washing, release and re-capture on streptavidin beads for ultra-clean signal
  3. Signal quantitation via qPCR or NGS (for multiplex assays)

Key Capabilities

  • Attomolar-level sensitivity to detect down to ≈10 aM
  • High multiplexing with current panels detecting 200+ targets, custom panels available
  • Fully automated workflow to reduce hands-on time and improve consistency
  • Broad sample compatibility for plasma, serum, CSF, cell culture supernatants

Why It Matters

  • Captures lowest-abundance proteins, including cytokines, chemokines, and neurodegenerative markers—many below pico­gram levels
  • High dynamic range and reproducibility, outpacing legacy immunoassays and mass spectrometry in quantifying hard-to-access biomarkers
  • Ideal for early disease detection, immune profiling, biomarker discovery & validation—empowering confident scientific decisions.

Partner With Us

Working with Allumiqs means stepping into a powerful ecosystem designed to put customer success at the forefront. With a passionate team of scientists and a growing network of world-class channel partners, Allumiqs delivers more than just expertise—it fosters collaboration, transparency, and tailored solutions, making complex challenges feel simple.

  • Collaborative analysis: work with our team of experts on interpretation, publishing, and regulatory compliance.
  • Expertise in assay design and quality control ensures reliable performance.
  • Advanced automation delivers throughput and reproducibility.
  • Custom assay development from small panels to high‑plex coverage.

Get Started Today

Unlock the future of biomarker analysis with our High Sensitivity Biomarker Assay powered by ARGO™ HT + NULISA™. Whether you’re validating candidate proteins or profiling complex immune signatures, achieve unprecedented sensitivity and multiplexing in one platform.

Contact us to discuss sample types, panel customization, pricing, and timelines.

Related Capabilities

Lipidomics

In-depth profiling of many classes of biologically relevant lipids using our high resolution instruments.

Learn more

Multiomics

See the big picture by combining proteomics, lipidomics and metabolomics data.

Learn more

Metabolomics

Sample profiling using either untargeted metabolomics or selected panels of targeted metabolites is the best technique.

Learn more

Data Analytics

We help customers unlock the value and potential of their data with clearer, deeper insights.

Learn more

Let’s connect

Get in touch with our experts

Allumiqs Icon