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MagReSyn® Streptavidin MS (Mass Spectrometry)

$480.00$1,447.00

MagReSyn Streptavidin magnetic beads contain covalently coupled streptavidin for the enrichment of biotinylated molecules. The porous nature of the polymer technology allows for exceptional streptavidin capacity, translating into increased power for the immobilization/capture of biotinylated biomolecules. The high streptavidin load allows the use of as little as 10 µl beads, improving experimental miniaturization for high-throughput automated analysis. 

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Description

Ultra-capacity for capture of biotinylated molecules specifically for Mass Spectrometry workflows with reduced streptavidin peptides

MagReSyn® Streptavidin MS (Mass Spectrometry), is specifically designed to cater for applications in proteomics requiring on-bead enzymatic digestion of proteins using LysC and/or Trypsin, such as BioID. This is achieved through the chemical modification of lysine and arginine residues of Streptavidin as previously described by Rafiee et al (2020). The chemical modification of these residues has been optimized to retain a high affinity for Biotin, retaining over 80% of the capacity of our standard Streptavidin product, but with multiple-fold decreases in the release of streptavidin peptides resulting from on-bead digestion. For the latest MS compatible conditions please consult ReSyn Biosciences’ Method Library, and find relevant references by selecting “Streptavidin” from the product menu, and “on-bead” from the digestion menu.

Support: Proprietary polymer microparticles containing iron oxide (magnetite) with immobilised Streptavidin
Binding capacity (DNA): > 25 000 pmoles.ml-1 (Biotinylated oligo, 25-mer)
Binding capacity (Protein): > 2.5 mg.ml-1 (Biotinylated IgG)
Bead size: ~5-10 µm average
Formulation: 10 mg.ml-1 suspension in sodium phosphate buffer

*Allumiqs only distributes MagResyn products in Canada and United States. If you are not located in these regions, please visit the MagResyn website for more information.

Additional information

Sizes Available

2 mL, 5 mL, 10 mL

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